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Title   암 환자에서 Ibuprofen ( Motrin ) 의 부가적 진통 효과 ( The Additive Analgesic Effect of Ibuprofen ( Motrin ) in the Pain Control of the Cancer Patients )
Publicationinfo   1987 Jan; 019(02): 114-119.
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Abstract   We have studied the additive analgesic effect of Ibuprofen (Motrin) to other analgesics, such as Acetaminophen, Codeine, and Morphine Tincture, in 29 cancer patients with pain. Ibuprofen was administered 600 mg every 6 hour orally in addition to the other 3 drugs. Ibuprofen had additive analgesic effect only in mild or moderate pain (effectivity 77.8%) but not in severe pain. The drug was more effective in localized pain than in systemic pain (p<0.002), but the reported superiority of the drug in bone pain could not be confirmed. The adverse effects of Ibuprofen was minimal in frequency and severity. In twenty six of the 29 studied patients (89.7%), the pain could be controlled with these 4 drugs, alone or in combination.
저 자   이민상(Min Sang Yi),전영수(Young Soo Jun),문한림(Han Lim Moon),홍영선(Young Seon Hong),김훈교(Hoon Kyo Kim),김호연(Ho Yun Kim),이경식(Kyung Shik Lee),김동집(Dong Jip Kim)